The Matrix: reality and relevance

A key question that appears in movies like "The Matrix" and alike is: What is real?, or What is reality? . An answer to that question is totally out of our reach, and not really useful. The appropriate question for me is:

What is relevant?

This question will always give us light about where we are and will lead us to a definite and suitable course of action. In the end, it doesn't matter if we are living in a selaed simulation. It only matters what is at our reach. It only matters what we can understand and influence.